Peer-reviewed veterinary case report
How diet affects heart health and taurine in 4 dog breeds
By Adin, Darcy et al.·Published in Journal of veterinary internal medicine·2021·University of Florida, United States·View original on PubMed →
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Original publication title: Effect of type of diet on blood and plasma taurine concentrations, cardiac biomarkers, and echocardiograms in 4 dog breeds.
- Species:
- dog
Plain-English summary
A study looked at 188 healthy dogs, including breeds like Doberman Pinschers and Golden Retrievers, to see how their diets affected heart health. Dogs on grain-free diets showed higher levels of a heart protein (hs-cTnI) that can indicate heart muscle injury compared to those on grain-inclusive diets. Similarly, dogs eating diets with certain controversial ingredients (like peas or potatoes) also had higher levels of this protein and a greater chance of heart rhythm issues. While no major heart problems were found, these findings suggest that certain diets might be linked to subtle heart changes.
People also search for: dog grain-free diet heart problems · Doberman heart health diet · Golden Retriever diet and heart disease
Abstract
BACKGROUND: Associations of diet with dilated cardiomyopathy are under investigation. OBJECTIVES: That cardiac assessment would show abnormalities in healthy dogs eating grain-free (GF) diets or diets with Food and Drug Administration (FDA)-listed ingredients of concern (peas, lentils, or potatoes) as top 10 ingredients (FDA-PLP), but not in dogs eating grain-inclusive (GI) diets or diets without FDA-listed ingredients of concern (PLP) in the top 10 ingredients (NoFDA-PLP). ANIMALS: One hundred eighty-eight healthy Doberman Pinschers, Golden Retrievers, Miniature Schnauzers, and Whippets. METHODS: This study was an observational cross-sectional study. Echocardiograms, cardiac biomarkers, and blood and plasma taurine concentrations were compared between dogs eating GF (n = 26) and GI (n = 162) diets, and between FDA-PLP (n = 39) and NoFDA-PLP (n = 149) diets, controlling for age and breed. Demographic characteristics, murmurs, genetic status, and ventricular premature complexes (VPCs) during examination were compared between dogs eating different diet types. RESULTS: No differences in echocardiographic variables, N-terminal pro-B-type natriuretic peptide or whole blood taurine were noted between dogs eating different diet types. Dogs eating GF diets had higher median high-sensitivity cardiac troponin I (hs-cTnI) (GF 0.076 ng/mL [Interquartile range (IQR), 0.028-0.156] vs. GI 0.048 [IQR, 0.0026-0.080]; P < .001) and higher median plasma taurine (GF 125 nmol/mL [IQR, 101-148] vs GI 104 [IQR, 86-123]; P = .02) than dogs eating GI diets. Dogs eating FDA-PLP diets had higher median hs-cTnI (0.059 ng/mL [IQR, 0.028-0.122]) than dogs eating NoFDA-PLP diets (0.048 [IQR, 0.025-0.085]; P = .006). A greater proportion of dogs eating FDA-PLP diets (10%) had VPCs than dogs eating NoFDA-PLP diets (2%; P = .04). CONCLUSIONS AND CLINICAL IMPORTANCE: Higher hs-cTnI in healthy dogs eating GF and FDA-PLP diets might indicate low-level cardiomyocyte injury.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33638176/