Peer-reviewed veterinary case report
Recombinant distemper vaccine protects shelter dogs exposed right
By Larson, L J & Schultz, R D·Published in Veterinary therapeutics : research in applied veterinary medicine·2006·Department of Pathobiological Sciences, United States·View original on PubMed →
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Original publication title: Effect of vaccination with recombinant canine distemper virus vaccine immediately before exposure under shelter-like conditions.
- Species:
- dog
Plain-English summary
A group of dogs was vaccinated with a new type of canine distemper virus (CDV) vaccine just hours before being exposed to the virus in a high-risk environment. The vaccinated dogs did not get sick, while unvaccinated dogs became ill and unfortunately died. Dogs that received the vaccine a week before exposure also stayed healthy. This study suggests that the new vaccine can provide quick protection against CDV, making it a good option for dogs in shelters or kennels.
People also search for: dog distemper vaccine effectiveness · puppy vaccination before exposure · canine distemper virus symptoms
Abstract
Vaccination with modified-live virus (MLV) canine distemper virus (CDV) vaccine has historically been recommended for animals in high-risk environments because of the rapid onset of immunity following vaccination. Recombinant CDV (rCDV) vaccine was deemed a suitable alternative to MLV-CDV vaccination in pet dogs, but insufficient data precluded its use where CDV was a serious threat to puppies, such as in shelters, kennels, and pet stores. In this study, dogs experimentally challenged hours after a single dose of rCDV or MLV vaccine became sick but recovered, whereas unvaccinated dogs became sick and died. Dogs vaccinated with a single dose of rCDV or MLV vaccine 1 week before being experimentally challenged remained healthy and showed no clinical signs. Dogs given one dose of rCDV vaccine hours before being placed in a CDV-contaminated environment did not become sick. These findings support the hypothesis that rCDV vaccine has a similar time-to-immunity as MLV-CDV vaccines and can likewise protect dogs in high-risk environments after one dose.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16871493/