Peer-reviewed veterinary case report
Effect of weight loss on inflammatory biomarkers in obese dogs.
- Journal:
- Veterinary journal (London, England : 1997)
- Year:
- 2012
- Authors:
- Tvarijonaviciute, Asta et al.
- Affiliation:
- Department of Animal Medicine and Surgery · Spain
- Species:
- dog
Plain-English summary
This study looked at how losing weight affects certain markers of inflammation in dogs that are overweight. The dogs in the study lost about 2.5% of their body weight each week, which led to improvements in their overall health, including better fat levels and lower blood sugar markers. While some markers related to inflammation stayed normal during their weight loss, the levels of a protein called adiponectin increased, indicating that these dogs might be less likely to experience inflammation related to obesity. Overall, the findings suggest that weight loss can be beneficial for obese dogs in terms of reducing their risk of inflammation.
Abstract
The objective of this study was to evaluate the effects of weight loss on selected serum inflammatory biomarkers in obese dogs. An experimentally induced bodyweight reduction of approximately 2.5%/week was accompanied by significant decreases in metabolic markers of obesity (lipidic profile, fructosamine, and insulin-like growth factor-1). The concentrations of acute phase proteins and of selected cytokines remained within reference ranges in obese dogs during weight loss, suggesting that significant inflammation was not a major component of this experimental model. However, adiponectin concentrations increased following the period of weight loss suggesting reduced susceptibility of these animals to obesity-related inflammation.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/22464400/