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Peer-reviewed veterinary case report

Cefovecin injection treats cat abscesses and infected wounds safely

By Six, Robert et al.·Published in Journal of the American Veterinary Medical Association·2009·Pfizer Animal Health, United States·View original on PubMed

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Original publication title: Effectiveness and safety of cefovecin sodium, an extended-spectrum injectable cephalosporin, in the treatment of cats with abscesses and infected wounds.

Species:
cat

Plain-English summary

A group of cats with abscesses and infected wounds were treated with either a single injection of cefovecin or a daily oral medication called cefadroxil for two weeks. Both treatments were found to be effective, with 97% of the cats given cefovecin and 91% of those on cefadroxil showing improvement by the end of the study. There were no serious side effects reported from either treatment. This suggests that cefovecin is a safe and effective option for treating skin infections in cats.

People also search for: cat abscess treatment · cefovecin for cats · infected wound in cat care

Abstract

OBJECTIVE: To evaluate the effectiveness and safety of cefovecin sodium in the treatment of cats with naturally occurring skin infections (abscesses and infected wounds). DESIGN: Multicenter (26 sites), randomized, double-blind, controlled clinical trial. ANIMALS: Client-owned cats of any breed with naturally occurring skin infections with associated clinical signs and confirmatory bacteriologic culture results. PROCEDURES: Cats with clinical signs of skin and soft tissue infection were randomly allocated to receive a single dose of cefovecin (8 mg/kg [3.6 mg/lb], SC) followed by placebo drops administered orally once daily for 14 days or 1 SC placebo injection followed by cefadroxil (22 mg/kg [10 mg/lb], PO, once daily for 14 days). Only one 14-day treatment course was permitted. RESULTS: Effectiveness of cefovecin in the treatment of cats with abscesses and infected wounds was similar to that of cefadroxil. At the final assessment on day 28, 97% (86/89) of cefovecin-treated cats and 91% (80/88) of cefadroxil-treated cats were considered treatment successes. There were no serious adverse events or deaths related to treatment. CONCLUSIONS AND CLINICAL RELEVANCE: 1 SC injection of 8 mg of cefovecin/kg for the treatment of cats with naturally occurring skin infections (wounds and abscesses) was safe and as effective as cefadroxil administered orally at 22 mg/kg, once daily for 14 days.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19119969/