Peer-reviewed veterinary case report
Freeze-dried Lactobacillus fermentum probiotic boosts healthy gut
By Strompfová, V et al.Ā·Published in Folia microbiologicaĀ·2012Ā·Institute of Animal PhysiologyĀ·View original on PubMed ā
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Original publication title: Effectivity of freeze-dried form of Lactobacillus fermentum AD1-CCM7421 in dogs.
- Species:
- dog
Plain-English summary
A group of dogs received a freeze-dried probiotic called Lactobacillus fermentum AD1-CCM7421 to see how it affected their gut health. After taking the probiotic for one to two weeks, the dogs showed an increase in beneficial bacteria and a decrease in harmful bacteria in their feces. The treatment also led to higher levels of short-chain fatty acids, which are good for digestion, and did not cause any issues with stool consistency. Overall, the probiotic seemed to improve gut health in the dogs, and the benefits continued even after they stopped taking it.
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Abstract
The impact of probiotic supplementation of canine-derived strain Lactobacillus fermentum AD1-CCM7421 in freeze-dried form on quantitative composition of microbiota and short-chain fatty acid profile in feces of dogs was demonstrated by two independent studies (straightforward repeated-measures model; study I: a dose of 2 g per dog for 2 weeks, 10(8) CFU/g, n = 12; study II: 1 g per dog for 1 week, 10(7) CFU/g, n = 11. The results revealed a significant increase of lactic acid bacteria population persisting also after the cessation of probiotic application in both studies. A reduction of clostridia (study I, p (sum) < 0.01) and tested Gram-negative bacterial genera (coliforms, Aeromonas sp., Pseudomonas sp., study II, p < 0.05) was also detected. The strain AD1-CCM7421 colonized the canine digestive tract in sufficient numbers (10(5)-10(6) CFU/g) and it persisted in the majority of dogs after cessation of probiotic application. An increase of short-chain fatty acid concentrations (study I: butyric, succinic, valeric, formic acid) especially in the early post-treatment phase (p < 0.05) most likely led to a decrease of fecal pH value (p < 0.05) without negative influence on fecal consistency throughout the studies.
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Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22547329/