Peer-reviewed veterinary case report
How a triazole liposome affects immunity in vaccinated puppies
By Broshkov, M. & Kichun, I.·Published in BULGARIAN JOURNAL OF VETERINARY MEDICINE·2019·View original on Crossref →
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Original publication title: Effects of a 1,2,4-triazole derivative liposome emulsion on the innate and adaptive immunity of puppies vaccinated against canine parvovirus and canine distemper
- Species:
- dog
Plain-English summary
A group of puppies vaccinated against parvovirus and canine distemper received a special treatment called Trifuzol, which is a liposome emulsion. This treatment helped boost their immune systems by increasing certain immune cells and improving the activity of their neutrophils, which are important for fighting infections. However, the levels of antibodies against the viruses were lower in the puppies that received Trifuzol compared to those that were only vaccinated. Overall, Trifuzol showed promise as a way to enhance immunity in puppies and could be useful in veterinary practice.
People also search for: puppy vaccination immune support · Trifuzol for puppies · canine parvovirus treatment · boosting puppy immunity
Abstract
The aim of the study was the evaluate the immunomodulating effect of a 1,2,4-triazole derivative liposome emulsion (Trifuzol) in puppies vaccinated against parvovirus enteritis and canine distemper. The used Trifuzol liposome emulsion led to a significant increase in the absolute number of lympho-cytes and their immunoregulatory subpopulations, phagocytic activity of neutrophils. The level of antibodies against parvovirus enteritis (CPV) and canine distemper (CDV) in vaccinated and Trifuzol-treated puppies reached zero values which were statistically significantly lower than those in vac-cinated-only puppies (21.0 U/mL and 27.0 U/mL, respectively). It was concluded that the tested liposome emulsion of Trifuzol had an positive effect on the humoral immunity in puppies and can be used in clinical practice as an immunomodulatory agent.
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Search related cases →Original publication on Crossref: https://doi.org/10.15547/bjvm.2089