Peer-reviewed veterinary case report
How antibiotics and probiotics affect gut health in dogs after surgery
By Lucchetti, Brittany et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2021·Department of Small Animal Medicine and Surgery, United States·View original on PubMed →
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Original publication title: Effects of a perioperative antibiotic and veterinary probiotic on fecal dysbiosis index in dogs.
- Species:
- dog
Plain-English summary
A group of 20 dogs undergoing back surgery were given either a probiotic or a placebo to see if it would help their gut health after receiving antibiotics. While the dogs that received the placebo showed a decrease in a certain type of bacteria, those given the probiotic did not see any improvement in their gut health. Overall, the probiotic did not help the dogs recover their gut balance after surgery. More research is needed to understand how antibiotics affect dogs' gut health in the long run.
People also search for: dog gut health after surgery · probiotics for dogs on antibiotics · effects of antibiotics on dog microbiome
Abstract
Although widely used, the effects of perioperative antibiotics on the gastrointestinal microbiome are still being researched. The role of probiotics to ameliorate adverse effects of perioperative antibiotics is unclear. The dysbiosis index (DI), based on a quantitative polymerase chain reaction (qPCR) technique, is used to assess gastrointestinal health. The DI in dogs receiving perioperative antibiotics and the effects of concurrent probiotics were evaluated in this study. This was a prospective study of 20 dogs undergoing hemilaminectomy. Baseline and 48-hour postoperative fecal DI were evaluated. Eleven dogs received a probiotic and 9 received placebo. Preanesthetic DI was not different between treatment groups (= 0.378). One bacterial group,, decreased in the placebo group (= 0.002); however, there was no change in the probiotic group (= 0.336). The DI increased numerically after probiotic administration, but the time × treatment interaction was not significant (= 0.996). Administration of a probiotic failed to improve DI. Further investigation is needed to evaluate long-term effects of perioperative antibiotics on the gut microbiome.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33692578/