Peer-reviewed veterinary case report
Serum changes in cats after one methylprednisolone injection
By Sharkey, Leslie C et al.·Published in Veterinary clinical pathology·2007·Department of Veterinary Population Medicine, United States·View original on PubMed →
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Original publication title: Effects of a single injection of methylprednisolone acetate on serum biochemical parameters in 11 cats.
- Species:
- cat
Plain-English summary
A group of 11 adult cats with skin problems received a single injection of methylprednisolone acetate, a type of corticosteroid, to see how it affected their blood chemistry. After the treatment, some cats showed increased levels of certain substances in their blood, like albumin and bicarbonate, while others had different reactions. Overall, no serious side effects were reported, and the cats did not seem to have any negative reactions to the medication. This treatment can lead to noticeable changes in blood tests, but each cat may respond differently.
People also search for: cat skin problems treatment · corticosteroids for cats · cat blood test results after medication
Abstract
BACKGROUND: Therapeutic use of corticosteroids has been implicated in a variety of serum biochemical abnormalities in dogs; however, the effects in cats are less well characterized. OBJECTIVE: The objective of this brief communication is to report serum biochemical changes in response to methylprednisolone acetate (MPA) in adult cats. METHODS: Serum biochemical profiles were performed on 11 cats with dermatologic diseases at baseline, 3-6 days, and 16-24 days after a single intramuscular dose of 5 mg/kg MPA. RESULTS: Median serum albumin and bicarbonate concentrations and amylase activity were increased compared to baseline at both post-treatment time points; aspartate aminotransferase activity and magnesium concentration were increased at 3-6 days post-treatment only; and alkaline phosphatase activity and total calcium concentration were increased at 16-24 days post-treatment only. Median serum creatinine concentration was decreased compared to baseline at both post-treatment time points. Examination of data from individual cats revealed significant variability in serum biochemical changes in response to MPA. No adverse clinical reactions to the drug were reported. CONCLUSIONS: A single dose of MPA results in significant changes in some serum biochemical values in cats, although individual responses will vary.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17523093/