Peer-reviewed veterinary case report
How body weight affects vaccine antibody levels in adult dogs
By Taguchi, Masayuki et al.·Published in Canadian journal of veterinary research = Revue canadienne de recherche veterinaire·2012·Taguchi Animal Hospital, Japan·View original on PubMed →
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Original publication title: Effects of body weight on antibody titers against canine parvovirus type 2, canine distemper virus, and canine adenovirus type 1 in vaccinated domestic adult dogs.
- Species:
- dog
Plain-English summary
A study looked at how body weight affects the levels of protective antibodies in adult dogs after vaccination against diseases like parvovirus, distemper, and adenovirus. Researchers tested nearly 1,000 dogs aged 2 to 6 years that had received a combination vaccine about a year earlier. They found that all weight groups had enough antibodies to protect against infection, but lighter dogs had significantly higher levels of antibodies against parvovirus and distemper compared to heavier dogs. This suggests that body weight may influence how well vaccines work in dogs.
People also search for: dog vaccination effectiveness by weight · why is my dog not responding to vaccines · canine parvovirus vaccine levels
Abstract
The objective of this study was to determine whether post-vaccination antibody titers vary according to body weight in adult dogs. Antibody titers against canine parvovirus type 2 (CPV-2), canine distemper virus (CDV), and canine adenovirus type 1 (CAdV-1) were measured for 978 domestic adult dogs from 2 to 6 y of age. The dogs had been vaccinated approximately 12 mo earlier with a commercial combination vaccine. The dogs were divided into groups according to their weight. It was found that mean antibody titers in all weight groups were sufficient to prevent infection. Intergroup comparison, however, revealed that CPV-2 antibody titers were significantly higher in the Super Light (< 5 kg) group than in the Medium (10 to 19.9 kg) and Heavy (> 20 kg) groups and were also significantly higher in the Light (5 to 9.9 kg) group than in the Heavy group. Antibody titers against CDV were significantly higher in the Super Light, Light, and Medium groups than in the Heavy group. There were no significant differences among the groups for the CAdV-1 antibody titers.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23543958/