Peer-reviewed veterinary case report
How different parvovirus strains affect dog parvovirus test results
By Markovich, Jessica E et al.·Published in Journal of the American Veterinary Medical Association·2012·VCA Animal Referral and Emergency Center of Arizona, United States·View original on PubMed →
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Original publication title: Effects of canine parvovirus strain variations on diagnostic test results and clinical management of enteritis in dogs.
- Species:
- dog
Plain-English summary
A group of 72 dogs showing signs of severe vomiting and diarrhea were tested for canine parvovirus (CPV) at a veterinary hospital. Out of these, 56 dogs tested positive for CPV, with the majority identified as having CPV type-2c or type-2b. The study found that both strains posed similar health risks, meaning that knowing the specific strain didn't change how the dogs were treated. Most dogs received supportive care, and the tests used were effective in diagnosing the infection.
People also search for: dog vomiting diarrhea treatment · canine parvovirus symptoms · CPV strain differences in dogs
Abstract
OBJECTIVE: To estimate the prevalence of canine parvovirus (CPV) strains among dogs with enteritis admitted to a referral hospital in the southwestern United States during an 11-month period and to compare diagnostic test results, disease severity, and patient outcome among CPV strains. DESIGN: Prospective observational study. ANIMALS: 72 dogs with histories and clinical signs of parvoviral enteritis. PROCEDURES: For each dog, a fecal sample or rectal swab specimen was evaluated for CPV antigen via an ELISA. Subsequently, fecal samples (n = 42 dogs) and pharyngeal swab specimens (16) were obtained and tested for CPV antigen via an ELISA and CPV DNA via a PCR assay. For specimens with CPV-positive results via PCR assay, genetic sequencing was performed to identify the CPV strain. RESULTS: 56 dogs tested positive for CPV via ELISA or PCR assay. For 42 fecal samples tested via both ELISA and PCR assay, 27 had positive results via both assays, whereas 6 had positive PCR assay results only. Ten pharyngeal swab specimens yielded positive PCR assay results. Genetic sequencing was performed on 34 fecal or pharyngeal swab specimens that had CPV-positive PCR assay results; 25 (73.5%) were identified as containing CPV type-2c, and 9 (26.5%) were identified as containing CPV type-2b. No association was found between CPV strain and disease severity or clinical outcome. CONCLUSIONS AND CLINICAL RELEVANCE: CPV type-2b and CPV type-2c posed similar health risks for dogs; therefore, genetic sequencing of CPV does not appear necessary for clinical management of infected patients. The diagnostic tests used could detect CPV type-2c.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22720989/