Peer-reviewed veterinary case report
Cetirizine does not reduce itching in dogs with chronic atopic
By Hsiao, Yun-Hsia et al.·Published in Journal of veterinary science·2016·Asian Referral Center·View original on PubMed →
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Original publication title: Effects of cetirizine in dogs with chronic atopic dermatitis: a randomized, double blind, placebo-controlled trial.
- Species:
- dog
Plain-English summary
A group of dogs with chronic itching due to atopic dermatitis (a skin allergy) was given either cetirizine, an allergy medication, or a placebo for two weeks to see if it would help relieve their symptoms. Unfortunately, after 14 days, there was no noticeable improvement in itching for the dogs taking cetirizine compared to those on the placebo. This suggests that cetirizine and similar allergy medications may not be effective for managing long-term itching in dogs with allergies.
People also search for: dog itching treatment · cetirizine for dogs allergies · chronic dermatitis in dogs
Abstract
This study was conducted to evaluate the effects of cetirizine in dogs with atopic dermatitis (AD) while fulfilling Favrot's diagnostic clinical criteria. Dogs received either 3 mg/kg cetirizine (n = 27), or a placebo (n = 23) orally once daily for 14 days in a randomized, double blind, placebo-controlled study, without concomitant medication. The effects were evaluated using a pruritus visual analog scale at the start (day 0) and at day 14. After 14 days, cetirizine clearly had no effect on the pruritus in dogs with chronic AD, and there was no significant difference between groups. These findings indicated that cetirizine (and likely H1 histamine receptor antagonists in general) should not be recommended for the control of pruritus in dogs with long term allergies.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27297415/