Peer-reviewed veterinary case report
Periodontal bone and cementum healing in dogs with enamel matrix
By Shirakata, Yoshinori et al.·Published in The International journal of periodontics & restorative dentistry·2013·Department of Periodontology, Japan·View original on PubMed →
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Original publication title: Effects of enamel matrix derivative and basic fibroblast growth factor with μ-tricalcium phosphate on periodontal regeneration in one-wall intrabony defects: an experimental study in dogs.
- Species:
- dog
Plain-English summary
A group of dogs with gum disease had specific bone defects treated with different combinations of a bone-building material and growth factors to see which helped heal their gums better. The treatment that combined enamel matrix derivative, basic fibroblast growth factor, and a calcium phosphate material showed the best results in helping the dogs regenerate gum tissue. While all treatments helped to some extent, the combination treatment was particularly effective in promoting new cementum formation, which is important for healthy gums.
People also search for: dog gum disease treatment · periodontal regeneration in dogs · enamel matrix derivative for dogs
Abstract
This study evaluated the effects of enamel matrix derivative (EMD) and basic fibroblast growth factor (bFGF) with μ-tricalcium phosphate (μ-TCP) on periodontal healing in intrabony defects in dogs. One-wall intrabony defects created in dogs were treated with μ-TCP alone (μ-TCP), EMD with μ-TCP (EMD/μ-TCP), bFGF with μ-TCP (bFGF/μ-TCP), and a combination of each (EMD/bFGF/μ-TCP). The amount of new bone formation was not significant for any group. The EMD/bFGF/μ-TCP group induced significantly greater new cementum formation than the μ-TCP and bFGF/μ-TCP groups and, although not significantly, formed more new cementum than the EMD/μ-TCP group. These findings indicate that EMD/bFGF/μ-TCP treatment is effective for cementum regeneration.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23998160/