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Peer-reviewed veterinary case report

Effects of exogenous glycosaminoglycans on the histological structure of the rat bladder in experimental cystitis.

Journal:
Bulletin of experimental biology and medicine
Year:
2012
Authors:
Sobolev, V E
Affiliation:
St. Petersburg State Academy of Veterinary Medicine
Species:
rodent

Abstract

The protective effects of a complex glycosaminoglycan preparation in doses of 50 and 100 mg/kg were studied in experimental cystitis induced in rats by administration of 9% acetic acid. Daily glycosaminoglycan intake for 2 weeks before intrabladder injection of acetic acid resulted in a less severe injury to the bladder mucosa in comparison with controls receiving no glycosaminoglycans.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/23330103/