Peer-reviewed veterinary case report
Isoflurane needs in dogs during ear surgery with two pain drug combos
By Van Wijnsberghe, Anne-Sophie et al.·Published in Veterinary anaesthesia and analgesia·2020·Anesthé·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Effects of fentanyl-lidocaine-ketamine versus sufentanil-lidocaine-ketamine on the isoflurane requirements in dogs undergoing total ear canal ablation and lateral bulla osteotomy.
- Species:
- dog
Plain-English summary
A group of 20 dogs undergoing surgery to remove their ear canals and treat ear infections were given two different combinations of pain medications during the procedure. One group received a mix of sufentanil, lidocaine, and ketamine, while the other group received fentanyl, lidocaine, and ketamine. The dogs that received the sufentanil mix needed less isoflurane (an anesthetic gas) and showed better recovery and less pain after waking up from surgery compared to those that received fentanyl. This suggests that the sufentanil combination may be a better option for pain management in these types of surgeries.
People also search for: dog ear surgery recovery · pain management for dogs · isoflurane anesthesia in dogs
Abstract
OBJECTIVE: To compare the isoflurane-sparing effects of sufentanil-lidocaine-ketamine (SLK) and fentanyl-lidocaine-ketamine (FLK) infusions in dogs undergoing total ear canal ablation and lateral bulla osteotomy (TECA-LBO). STUDY DESIGN: Randomized blinded clinical study. ANIMALS: A group of 20 client-owned dogs undergoing TECA-LBO. METHODS: Intravenous (IV) administration of lidocaine (3 mg kg) and ketamine (0.6 mg kg) with fentanyl (5.4 μg kg; n = 10; FLK group) or sufentanil (0.72 μg kg; n = 10; SLK group) was immediately followed by the corresponding constant rate infusion (CRI) (lidocaine 3 mg kghour; ketamine 0.6 mg kghour; either fentanyl 5.4 μg kghouror sufentanil 0.72 μg kghour). Anaesthesia was induced with propofol 3-5 mg kgIV and was maintained with isoflurane. End-tidal isoflurane concentration (Fe'Iso) was decreased in 0.2% steps every 15 minutes until spontaneous movements were observed (treated with propofol 1 mg kgIV) or an increase of > 30% in heart rate or mean arterial pressure from baseline occurred (treated with rescue fentanyl or sufentanil). Quality of recovery and pain were assessed at extubation using the short-form Glasgow Composite Pain Scale (SF-GCPS), Colorado State University Canine Acute Pain scale (CSU-CAP), and visual analogue scale (VAS). Data were analysed with analysis of variance, t tests, Fisher test and Spearman coefficient (p < 0.05). RESULTS: Fe'Iso decreased significantly in SLK group (45%; p = 0.0006) but not in FLK (15%; p = 0.1135) (p = 0.0136). SLK group had lower scores for recovery quality (p = 0.0204), SF-GCPS (p = 0.0071) and CSU-CAP (p = 0.0273) than FLK at extubation. Intraoperative rescue analgesia and VAS were not significantly different between groups. CONCLUSIONS AND CLINICAL RELEVANCE: Compared with FLK infusion, CRI of SLK at these doses decreased isoflurane requirements, decreased pain scores and improved recovery quality at extubation in dogs undergoing TECA-LBO.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32792272/