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Peer-reviewed veterinary case report

Meloxicam does not affect bleeding in dogs during orthopedic surgery

By Kazakos, G M et al.·Published in The Veterinary record·2005·Department of Clinical Studies·View original on PubMed

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Original publication title: Effects of meloxicam on the haemostatic profile of dogs undergoing orthopaedic surgery.

Species:
dog
Movement & jointsDogs

Plain-English summary

A group of 38 dogs undergoing orthopedic surgery were given meloxicam, a common pain relief medication, to see how it affected their blood clotting during and after the procedure. The dogs received different doses and methods of administration, but overall, there were no significant changes in their bleeding times or clotting profiles. One group did show a slight increase in a specific clotting measurement after surgery, but all results remained within normal limits. This suggests that meloxicam can be safely used in dogs undergoing surgery without negatively impacting their ability to clot blood.

People also search for: dog surgery bleeding risk · meloxicam for dogs · dog pain medication safety

Abstract

The buccal mucosal bleeding time (BMBT), prothrombin time (PT), activated partial thromboplastin time (APTT) and intraoperative bleeding score (IBS) of 38 dogs that underwent orthopaedic surgical procedures and received meloxicam orally and/or parenterally were measured. Fourteen of the dogs (group A) received a single subcutaneous dose of 0.2 mg/kg meloxicam at premedication, 18 dogs (group B) received 0.1 mg/kg meloxicam orally daily for five days followed by a single subcutaneous dose of 0.2 mg/kg meloxicam preoperatively, and six dogs (group C) received 0.5 ml of normal saline subcutaneously at premedication. No statistically significant differences among the groups were detected in relation to the mean (SD) values of BMBT, PT and IBS before and after the surgery, or in the values of APTT in group A. In group B there was a small but significant increase in APTT after the surgery, but all the measurements were within the normal range for dogs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16215245/