Peer-reviewed veterinary case report
Effects of mesenchymal stem cells isolated from amniotic fluid and platelet-rich plasma gel on severe decubitus ulcers in a septic neonatal foal.
- Journal:
- Research in veterinary science
- Year:
- 2012
- Authors:
- Iacono, E et al.
- Affiliation:
- Department of Veterinary Medical Sciences · Italy
- Species:
- horse
Plain-English summary
This study looked at how well certain treatments worked for severe bedsores (decubitus ulcers) in a very young foal that had an infection. The colt was hospitalized for 25 days, and for 15 of those days, he received different treatments: a mix of stem cells from amniotic fluid and a gel made from platelets, just the platelet gel, or aloe gel. The results showed that the combination of stem cells and platelet gel helped the sores heal faster than the other treatments. Even after seven months, the sore treated with aloe gel had not fully healed. Overall, the treatment with stem cells and platelet gel was the most effective.
Abstract
This paper documents the treatment of severe decubitus ulcers with amniotic fluid mesenchymal stem cells and platelets rich plasma (PRP) gel in a septic neonatal foal. The colt needed 25 days of hospitalization: during this period ulcers were treated for 15 days with mesenchymal stem cells (MSCs) plus PRP, PRP gel alone, or aloe gel. Healing was faster using MSCs+PRP, and at 7 months an ulcer treated with aloe gel was still not completely healed.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/22579411/