Peer-reviewed veterinary case report
Metoclopramide reduces vomiting in cats sedated with xylazine
By Kolahian, Saeed & Jarolmasjed, Seyedhosein·Published in Journal of feline medicine and surgery·2010·Department of Basic Sciences·View original on PubMed →
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Original publication title: Effects of metoclopramide on emesis in cats sedated with xylazine hydrochloride.
- Species:
- cat
Plain-English summary
A group of cats were given different doses of metoclopramide, a medication that helps prevent vomiting, before being sedated with xylazine. The results showed that metoclopramide significantly reduced how often the cats vomited after sedation. While the highest dose also helped the cats become sedated faster, all doses effectively lowered the vomiting frequency. This suggests that metoclopramide can be a useful option for preventing vomiting in cats undergoing sedation.
People also search for: cat vomiting after sedation · metoclopramide for cats · xylazine sedation side effects
Abstract
The prophylactic anti-emetic effect of five dosages of metoclopramide (0.2, 0.4, 0.6, 0.8 and 1mg/kg, IM) was evaluated against saline solution, both injected 1h before administration of xylazine in cats. Saline was administered to cats (day 0) followed by sequentially increasing dosages of metoclopramide at 1-week intervals. After xylazine injection, all cats were carefully observed to record the frequency of emesis and the time until onset of the first emetic episode. The onset of sedation in these cats was also studied. Prior treatment with each dosage of metoclopramide significantly reduced the frequency of emetic episodes (P<0.05). Metoclopramide administration prior to xylazine injection did not alter the time until onset of the first emetic episode at any of mentioned dosages, but significantly reduced the time until onset of sedation only at the dose of 1mg/kg. Metoclopramide may be used as a prophylactic anti-emetic in cats sedated with xylazine hydrochloride.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20817585/