Peer-reviewed veterinary case report
Canine metastatic lung tumor shrinks after neural stem cell
By Hwang, Yawon et al.·Published in Journal of veterinary science·2017·College of Veterinary Medicine, South Korea·View original on PubMed →
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Original publication title: Effects of neural stem cells and 5-fluorocytosine in canine metastatic lung tumor.
- Species:
- dog
Plain-English summary
A dog with metastatic lung tumors was treated with a combination of human neural stem cells and a chemotherapy drug called 5-fluorocytosine. About two weeks after starting treatment, the dog's lung nodules shrank in size and number, indicating a positive response to the therapy. While the treatment didn't significantly affect tumors in the dog's abdomen, it helped improve the dog's overall quality of life with fewer side effects compared to traditional chemotherapy options.
People also search for: dog lung tumor treatment · canine metastatic cancer therapy · 5-fluorocytosine for dogs
Abstract
This is the first case report to describe the tumor regressive effect of systemic human neural stem cell (NSC)/5-fluorocytosine (5-FC) therapy on canine metastatic lung tumor. The therapeutic effects appeared approximately two weeks after 5-FC administration. Thoracic radiographs revealed a reduced number of lung nodules and decreased nodule size. However, there were no significant antitumor effects on primary lesions in abdominal organs. In conclusion, human NSC/5-FC prodrug therapy can secure patient quality of life with the same or more therapeutic effects and fewer side effects than other recommended chemotherapies.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27515273/