Peer-reviewed veterinary case report
Effects of neural stem cells and 5-fluorocytosine in canine metastatic lung tumor.
- Journal:
- Journal of veterinary science
- Year:
- 2017
- Authors:
- Hwang, Yawon et al.
- Affiliation:
- College of Veterinary Medicine · South Korea
- Species:
- dog
Abstract
This is the first case report to describe the tumor regressive effect of systemic human neural stem cell (NSC)/5-fluorocytosine (5-FC) therapy on canine metastatic lung tumor. The therapeutic effects appeared approximately two weeks after 5-FC administration. Thoracic radiographs revealed a reduced number of lung nodules and decreased nodule size. However, there were no significant antitumor effects on primary lesions in abdominal organs. In conclusion, human NSC/5-FC prodrug therapy can secure patient quality of life with the same or more therapeutic effects and fewer side effects than other recommended chemotherapies.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/27515273/