Peer-reviewed veterinary case report
Hyperbaric oxygen effects on blood tests after dog pyometra surgery
By Degregori, Emanuelle Bortolotto et al.·Published in Topics in companion animal medicine·2025·Federal University of Santa Maria, Brazil·View original on PubMed →
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Original publication title: Effects of postoperative hyperbaric oxygen therapy on hematological and biochemical parameters in patients diagnoses with pyometra in sepsis.
- Species:
- dog
Plain-English summary
An 8-year-old female dog diagnosed with pyometra (a serious infection of the uterus) and sepsis was treated with surgery and hyperbaric oxygen therapy (HBOT) after her operation. The dog received three sessions of HBOT, which helped improve her blood cell counts significantly compared to dogs that did not receive this treatment. After the therapy, her red blood cells and white blood cells showed marked improvement, indicating a positive response to the treatment. This suggests that combining HBOT with surgery can be beneficial for dogs suffering from pyometra and sepsis.
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Abstract
The aim of this study was to evaluate the impact of hyperbaric oxygen therapy (HBOT) on hematologic and biochemical markers in dogs with pyometra in sepsis. Eighteen patients were equally distributed between the control group (CG) and the hyperbaric group (HG). All patients underwent ovariohysterectomy, supportive therapy, and insertion of a central venous catheter. HG attended three HBOT sessions (2 absolute atmospheres, 45 min) postoperatively. Blood tests were performed on admission, 1 h postoperatively, 24 h, 48 ​​h, and 72 h postoperatively. Both groups showed a significant reduction in red blood cells (Hm) and hematocrit (Hto) after surgery, but this effect was reversed after three HBO sessions and maintained in CG. Despite the initial reduction in hemoglobin (Hg) in HG, the values ​​increased again after the end of the protocol. A reduction of >50 % in leukocytes was noted in HG in the last evaluation in relation to the values ​​at admission. Significant reduction was also found for neutrophils, metamyelocytes and rods in HG. There was no difference in biochemical markers. HBO associated with OVH and supportive therapy can be considered in the treatment of pyometra, with rapid and marked improvement, after three sessions, in the e red blood cells and leukogram.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39675624/