Effects ofon broiler chicken coccidiosis: a systematic review and meta-analysis.

Abstract

Coccidiosis is a recurring disease in broiler flocks that causes significant economic losses. This study aims to evaluate the effect ofon coccidiosis in broilers through a systematic review and meta-analysis. The article selection process included a search from the year 2000 to February 2021, with no restrictions on country or geographical region. Our objective was met by only six studies, which underwent systematic review. The meta-analysis was conducted using the metafor package in R via RStudio (version 1.1.383; RStudio, Inc.). The systematic review indicates thatstudies have shown the effectiveness of various plant extracts (essential oil and methanolic extract) when administered in food or drinking water on the considered parameters (oocyst shedding, bloody diarrhoea, mortality rate, weight gain, conversion index, lesion score). Furthermore,studies demonstrated a positive impact on oocyst count, LC(lethal concentration), sporulation rate (%), and sporulation inhibition rate (%). The meta-analysis of the four studies included in this analysis revealed that the inclusion ofextract resulted in a significant reduction in oocyst shedding (SMD&#x2009;=&#x2009;-1.64, 95% CI: -2.72 to -0.55;&#x2009;<&#x2009;0.0001). However, the effectiveness ofextract was not as significant as that of antibiotics (SMD&#x2009;=&#x2009;0.57, 95% CI: -0.19 to 0.95;&#x2009;=&#x2009;0.0032). Various forms of administration and extracts ofhave demonstrated antiparasitic activity against, making them suitable as natural anticoccidial agents.