Effects ofon production performance and immunity of broiler chickens and their mechanism.

Abstract

INTRODUCTION: species have attracted more and more attention as a potential antibiotic substitute for human health and animal production due to their remarkable antibacterial effects. However, the underlying mechanism is unclear. This experiment's goal was to investigate the impacts of lactic acid bacteria (LAB) on the growth performance, carcass characteristics, immune function of broiler chickens and their mechanism. METHODS: One hundred and eighty 1-day-old AA broilers were used and randomly allocated into 3 treatment groups with 6 replicates of 10 chickens per replicate. The 3 treatment groups were control group (CK),added group (LAB-E, 1.0 &#xd7; 108 CFU/kg) for the first 7 days;added group (LAB-A, 1.0 &#xd7; 108 CFU/kg) for the whole experimental period. Broilers had free access to water and feed. RESULTS: The results showed that addition of L. acidophilus for the whole experimental period significantly decreased ADFI, FCR and the abdominal fat percentage of broilers (&#x202f;<&#x202f;0.05), tended to increase the levels of IgG in broiler serum (&#x202f;=&#x202f;0.093). The LAB-A group had higher HDL-C content and IL-2, IL-4 content, and lower level of LPS in broiler serum compared to the controls (&#x202f;<&#x202f;0.05). DISCUSSION: In conclusion,improved feed efficiency and immune function of broilers by controlling nutrient metabolism and inflammation responses of broilers.can be used as a potential substitute for antibiotics in broiler production.