Peer-reviewed veterinary case report
Osaterone and delmadinone both treat enlarged prostate in dogs
By Albouy, M et al.·Published in The Veterinary record·2008·Research and Development Department, France·View original on PubMed →
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Original publication title: Efficacies of osaterone and delmadinone in the treatment of benign prostatic hyperplasia in dogs.
- Species:
- dog
Plain-English summary
A group of dogs with benign prostatic hyperplasia (an enlarged prostate) were treated with either an oral medication called osaterone or an injection of delmadinone to see which worked better. Both treatments helped reduce symptoms and improve the dogs' condition, but osaterone was more effective at shrinking the prostate size faster. Throughout the study, both medications caused only minor side effects that went away quickly. Overall, both options are viable for treating this condition in dogs.
People also search for: dog enlarged prostate treatment · osaterone for dogs · delmadinone side effects in dogs
Abstract
A multicentre randomised clinical trial was performed to compare the therapeutic potential of osaterone acetate with that of delmadinone acetate in the treatment of benign prostatic hyperplasia in dogs. The osaterone was administered orally at 0.25 mg/kg bodyweight once a day for seven days to 73 dogs. The delmadinone was administered by a single intramuscular or subcutaneous injection at 3 mg/kg bodyweight to 69 dogs. During the 180-day trial, the dogs were monitored five times for their clinical signs and prostate volume. The two drugs were similarly effective in reducing the clinical signs and inducing complete clinical remission, and both induced a similar level of minor, mostly transitory adverse effects. Osaterone reduced the volume of the prostate glands of the dogs significantly more quickly than delmadinone.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18689779/