Peer-reviewed veterinary case report
How well oral fluralaner and spot-on moxidectin/imidacloprid treat
By Han, Hock Siew et al.·Published in Veterinary dermatology·2016·Han Veterinary Surgery·View original on PubMed →
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Original publication title: Efficacy and duration of action of oral fluralaner and spot-on moxidectin/imidacloprid in cats infested with Lynxacarus radovskyi.
- Species:
- cat
Plain-English summary
A group of 30 cats infested with a type of mite called Lynxacarus radovskyi were treated to see which method worked best. Some cats received a single oral dose of fluralaner, while others got two doses of a spot-on treatment containing moxidectin and imidacloprid two weeks apart. Both treatments successfully eliminated the mites within 28 days, and neither method showed a significant difference in effectiveness. However, re-infestation occurred by Day 56 for both groups. This means that either treatment can effectively clear the infestation and keep cats mite-free for at least 42 days after treatment.
People also search for: cat mite treatment · Lynxacarus radovskyi in cats · fluralaner for cat mites · moxidectin imidacloprid spot-on for cats
Abstract
BACKGROUND: Lynxacarus radovskyi has been observed in cats in Malaysia; previously treatment with fipronil and moxidectin/imidacloprid spot-on has been described. OBJECTIVES: To compare the efficacy of two spot-on treatments of moxidectin/imidacloprid, two weeks apart to a single oral dose of fluralaner against Lynxacarus radovskyi and evaluate time to re-infestation. METHODS: Thirty cats were assigned to three groups of ten cats each. Group 1 received one 250 mg fluralaner tablet. Group 2 received two doses of moxidectin/imidacloprid spot-on two weeks apart. Group 3 consisted of untreated controls. For each cat, three plucks of about 50 hairs each were collected from three sites (dorsal neck, lateral thigh and perineal/tail region) for a total of nine pluckings every two weeks. Severity of infestation was scored from 0 (no parasite), to 1 (only nonhatched eggs), 2 (both hatched and nonhatched eggs), 3 (<50 mites) and 4 (>50 mites). Efficacy was compared between treatment groups and over time in the same group, and results analysed statistically. Re-infestation was defined as the identification of new eggs or mites on hair pluckings. RESULTS: Moxidectin/imidacloprid spot-on and oral fluralaner achieved 100% eradication within 28 days. No significant difference was observed between groups 1 and 2; re-infestation occurred by Day 56 in both treatment groups. CONCLUSION: A single dose of oral fluralaner or two moxidectin/imidacloprid spot-on treatments two weeks apart are efficacious in the eradication of L. radovskyi in cats and able to prevent re-infestation for at least 42 days post-treatment.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27870235/