Peer-reviewed veterinary case report
Convenia injection cures dog urinary tract infections better than
By Passmore, C A et al.·Published in The Journal of small animal practice·2007·Pfizer Animal Health, United Kingdom·View original on PubMed →
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Original publication title: Efficacy and safety of cefovecin (Convenia) for the treatment of urinary tract infections in dogs.
- Species:
- dog
Plain-English summary
A group of 129 dogs with urinary tract infections was treated with either a single injection of cefovecin (Convenia) or a 14-day course of cephalexin (Rilexine). The results showed that cefovecin eliminated the bacteria causing the infection in about 90% of the dogs, while cephalexin was effective in only about 53%. Overall, 79% of the dogs treated with cefovecin were cured compared to just 36% with cephalexin. Both treatments were found to be safe, with no serious side effects reported.
People also search for: dog urinary tract infection treatment · cefovecin for dogs · cephalexin side effects in dogs
Abstract
OBJECTIVES: To determine the efficacy and safety of cefovecin (Convenia); Pfizer Animal Health) in the treatment of urinary tract infections in dogs. METHODS: A multi-centre, blinded, randomised study was conducted in 129 dogs with urinary tract infections. Cephalexin (Rilexine) administered twice daily at 15 mg/kg bodyweight orally for 14 days was compared with a single, subcutaneous injection of cefovecin (Convenia) in dogs. The primary efficacy parameter assessed was bacterial elimination of the pretreatment uropathogen. RESULTS: One hundred and twenty-nine dogs were included in efficacy assessments. Escherichia coli was eliminated in 90.5 per cent of cefovecin-treated dogs compared with 52.9 per cent of cephalexin-treated dogs (P=0.0004). Overall cure rates for dogs with Escherichia coli infections were 79.1 per cent for cefovecin and 36.4 per cent for cephalexin-treated dogs (P=0.0003). There were no suspected adverse drug reactions attributed to treatment with cefovecin or cephalexin. CLINICAL SIGNIFICANCE: Cefovecin was shown to be an effective and safe treatment for urinary tract infections.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17355604/