Peer-reviewed veterinary case report
Cefovecin injection for treating cat urinary tract infections safely
By Passmore, C A et al.·Published in The Journal of small animal practice·2008·Pfizer Animal Health·View original on PubMed →
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Original publication title: Efficacy and safety of cefovecin for the treatment of urinary tract infections in cats.
- Species:
- cat
Plain-English summary
A group of cats with urinary tract infections (UTIs) were treated with either a single injection of cefovecin or a 14-day course of oral cephalexin. The study found that cefovecin was effective in eliminating the bacteria causing the infections in about 76.7% of the cats, compared to 62.5% for cephalexin. Both treatments were safe, with no adverse reactions reported. This suggests that cefovecin is a good option for treating UTIs in cats.
People also search for: cat urinary tract infection treatment · cefovecin for cats · cephalexin side effects in cats
Abstract
OBJECTIVES: To determine the efficacy and safety of cefovecin (Convenia); Pfizer Animal Health) in the treatment of urinary tract infections in cats. METHOD: A multi-centre, masked, randomised study was conducted in cats presenting with clinical signs indicative of urinary tract infections. Cephalexin (Rilexine); Virbac) administered orally twice daily at 15 mg/kg bodyweight for 14 days was compared with a single subcutaneous injection of cefovecin in cats. The primary efficacy parameter assessed was bacterial elimination of the pretreatment uropathogen. RESULTS: Four hundred and thirty-four cats were screened for urinary tract infections. One hundred and eighty-five cats were treated with either cefovecin (n=124) or cephalexin (n=61). Ninety-seven cats (22.2 per cent) had confirmed bacteriuria and 82 cats were included in efficacy analysis. Escherichia coli was eliminated in 76.7 per cent (23 of 30) of cefovecin-treated cats compared with 62.5 per cent (10 of 16) of cephalexin-treated cats. Cefovecin demonstrated statistical non-inferiority compared with cephalexin for bacterial elimination. There were no suspected adverse drug reactions attributable to treatment with cefovecin or cephalexin. CLINICAL SIGNIFICANCE: Cefovecin was demonstrated to be an effective and safe treatment for urinary tract infections.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18422501/