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Peer-reviewed veterinary case report

Firocoxib improves lameness and pain in dogs with osteoarthritis

By Hanson, Peter D et al.·Published in Veterinary therapeutics : research in applied veterinary medicine·2006·Merial Limited, United States·View original on PubMed

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Original publication title: Efficacy and safety of firocoxib in the management of canine osteoarthritis under field conditions.

Species:
dog

Plain-English summary

A group of 249 dogs with osteoarthritis were treated with either firocoxib or etodolac for 30 days to see which medication worked better for their joint pain. Both medications were found to be effective, but firocoxib showed more improvement in reducing limping and pain during movement. Owners reported that their dogs seemed to feel better and move more comfortably while on firocoxib compared to etodolac. This suggests that firocoxib may be a better option for managing osteoarthritis in dogs.

People also search for: dog osteoarthritis treatment · firocoxib for dogs · dog limping pain relief

Abstract

A total of 249 client-owned dogs with osteoarthritis were treated with firocoxib (5 mg/kg/day) or a positive control, etodolac (10-15 mg/kg/day), for 30 days. Veterinary examinations were performed on approximately days 0 (visit 1), 14 (visit 2), and 29 (visit 3). Based on defined noninferiority criteria, firocoxib and etodolac were comparable. Based on the magnitude of the change from baseline, improvement with firocoxib was significantly greater than with etodolac for lameness at a trot (visits 2 and 3) and for lameness at a walk, pain on manipulation, and range of motion (visit 3) (P < .05). In weekly owner evaluations, firocoxib provided significantly greater improvement than etodolac (P < .05) at each scoring.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16871495/