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Peer-reviewed veterinary case report

Pain relief and safety of etodolac and butorphanol before dog spay

By Inoue, Tomohito et al.·Published in Journal of the American Animal Hospital Association·2006·Department of Veterinary Clinical Sciences, United States·View original on PubMed

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Original publication title: Efficacy and safety of preoperative etodolac and butorphanol administration in dogs undergoing ovariohysterectomy.

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Plain-English summary

Eighteen dogs were given either etodolac (a pain reliever), butorphanol (a sedative), or a combination of both before undergoing spay surgery (ovariohysterectomy). The dogs that received etodolac, alone or with butorphanol, showed lower pain scores after waking up from anesthesia compared to those that did not receive these medications. This means they seemed more comfortable and needed less pain relief during recovery. Overall, using etodolac and butorphanol together was effective in managing pain for these dogs during and after surgery.

People also search for: dog spay surgery pain relief · etodolac for dogs · butorphanol side effects in dogs

Abstract

Eighteen dogs undergoing ovariohysterectomy were premedicated with etodolac, butorphanol, or their combination. Various parameters, such as blood pressure, isoflurane requirements, behavioral pain scores, plasma cortisol concentration, plasma glucose concentration, and mucosal bleeding time, were assessed. The integrated plasma cortisol values were significantly lower in the etodolac and etodolac with butorphanol groups. Dogs receiving etodolac and butorphanol had the lowest behavioral pain scores from extubation until the end of monitoring. Isoflurane concentration over time (area under the curve), buccal mucosal bleeding time, and indices of renal function were not significantly different among the treatment groups.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16611929/