Peer-reviewed veterinary case report
Once-daily cephalexin works well for dog skin infections
By Toma, S et al.·Published in The Journal of small animal practice·2008·Ospedale Veterinario Cuneese, Italy·View original on PubMed →
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Original publication title: Efficacy and tolerability of once-daily cephalexin in canine superficial pyoderma: an open controlled study.
- Species:
- dog
Plain-English summary
A group of dogs with skin infections called superficial pyoderma were treated with an antibiotic called cephalexin. Some dogs received the medication once a day, while others took it twice a day. All the dogs showed improvement within 14 to 42 days, with most recovering around 28 days. A few dogs had mild side effects like vomiting or diarrhea, but these did not require stopping the treatment. Overall, the once-daily dosage was just as effective as the twice-daily dosage for treating the skin infections.
People also search for: dog skin infection treatment · cephalexin for dogs · dog vomiting after medication
Abstract
OBJECTIVES: The aims of this study were to evaluate the efficacy and tolerability of oral cephalexin given at 30 mg/kg once daily in dogs with superficial pyoderma and to compare them with those of oral cephalexin given at 15 mg/kg twice daily. METHODS: Twenty dogs with superficial pyoderma were treated with cephalexin at 30 to 60 mg/kg orally once daily (group A) and compared with 20 dogs treated at a dose of 15 to 30 mg/kg orally twice daily (group B). Dogs were treated until 14 days after clinical remission. Type and distribution of lesions, pruritus and general health status were assessed every 14 days using a numerical scale until 14 days after treatment discontinuation. Total scores for each evaluation day were compared between the two groups as well as time to obtain resolution and percentage of relapses. RESULTS: Resolution of superficial pyoderma was obtained in all dogs in 14 to 42 days (median 28 days for both groups), with no difference between groups. Six dogs experienced vomiting or diarrhoea but did not require discontinuation of the treatment. Only one dog (in group A) relapsed nine days after treatment discontinuation. CLINICAL SIGNIFICANCE: Once-daily cephalexin is as effective as twice-daily cephalexin in the treatment of canine superficial pyoderma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18631220/