Peer-reviewed veterinary case report
New topical treatment kills Echinococcus multilocularis in cats
By Tielemans, Eric et al.·Published in Veterinary parasitology·2014·Merial SAS, France·View original on PubMed →
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Original publication title: Efficacy in cats of a novel topical combination of fipronil, (S)-methoprene, eprinomectin, praziquantel, against induced infestations of Echinococcus multilocularis.
- Species:
- cat
Plain-English summary
A group of cats was tested for a parasitic infection called Echinococcus multilocularis, which can be harmful to both pets and humans. The cats were given a new topical treatment called Broadline, which combines several active ingredients to kill the parasites. After treatment, the studies showed that Broadline was 100% effective in eliminating the infection in the cats. This highlights the importance of regular deworming for cats, especially in areas where this parasite is common.
People also search for: cat deworming treatment · Echinococcus multilocularis in cats · Broadline for cat parasites
Abstract
Although foxes are the main reservoir of Echinococcus multilocularis, it is recognized that dogs and cats also may become infected. In cats the infection and egg production rates are usually low. Nevertheless, cats are a potential source of transmission of E. multilocularis. Due to the high human medical significance of E. multilocularis infection, it is important in endemic areas that owned cats are dewormed regularly. This paper presents the efficacy results of a new topical formulation, Broadline(®) (Merial) tested against E. multilocularis infection in cats. Two blinded laboratory studies were conducted to evaluate this novel topical combination of fipronil, (S)-methoprene, eprinomectin, and praziquantel against E. multilocularis. In each study, purpose-bred cats were assigned randomly to two treatment groups of 10 cats each: one untreated control group and one group treated at the minimum therapeutic dose of 0.12 mL/kg bodyweight to deliver 10mg fipronil, 12 mg (S)-methoprene, 0.5mg eprinomectin and 10mg praziquantel/kg bodyweight. The cats were inoculated orally with E. multilocularis protoscolices, 22 or 23 days before treatment. Based on necropsy and intestinal worm count, 8 or 11 days after treatment, the two studies confirmed 100% efficacy of Broadline(®) against adult E. multilocularis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24703072/