Peer-reviewed veterinary case report
Hydrocortisone spray helps manage itching in dogs with atopic
By Nuttall, Tim et al.·Published in Veterinary dermatology·2009·Small Animal Teaching Hospital, United Kingdom·View original on PubMed →
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Original publication title: Efficacy of a 0.0584% hydrocortisone aceponate spray in the management of canine atopic dermatitis: a randomised, double blind, placebo-controlled trial.
- Species:
- dog
Plain-English summary
A group of dogs with atopic dermatitis (a skin allergy) were treated with a hydrocortisone aceponate spray to see if it could help reduce their itching and skin irritation. After 28 days, the dogs receiving the spray showed a significant decrease in their symptoms compared to those getting a placebo. Most owners reported being satisfied with the results, and many dogs needed less frequent treatments as their condition improved. The spray was found to be safe, with no side effects noted, but it is not approved for long-term use.
People also search for: dog itching treatment · hydrocortisone spray for dogs · atopic dermatitis in dogs · dog skin allergy relief
Abstract
This study evaluated a 0.0584% hydrocortisone aceponate (HCA) spray (Cortavance; Virbac SA, Carros, France) in canine atopic dermatitis (AD). Initially, dogs with a canine AD extent and severity index (CADESI-03) >or= 50 were randomly allocated to receive HCA (n = 15) or placebo (n = 13) (two sprays from 10 cm away to treat an area of 100 cm(2)) once daily for 28 days. Twenty-one of the dogs then received HCA spray once daily, reducing to every other day or twice weekly over 42 days if improvement was maintained. CADESI, pruritus (14 cm visual-analogue-scale) and owner satisfaction (5-point scale) were recorded every 14 days. Haematology, biochemistry and adrenocorticotrophic hormone stimulation were performed at baseline, d28 and d70 (HCA n = 9; placebo n = 7). Intention-to-treat data were analysed. HCA spray significantly decreased CADESI (-61.4% versus -13.4%, P = 0.0069) and pruritus (-38.8% versus +57.6%, P = 0.0015) at d28 compared to placebo. Scores were significantly decreased at d14 (CADESI -50.5%, P < 0.0021) and d28 (CADESI P < 0.0001; pruritus P = 0.018) compared to baseline following HCA but not placebo. At d28 11 of 15 and 7 of 15 HCA dogs had >or= 50% reductions in CADESI and pruritus compared to 3 of 13 (P = 0.02) and 1 of 13 (P = 0.04) placebo dogs. Owner satisfaction scores were significantly higher in the HCA group (d28 P = 0.0001). Daily 3 of the 21 dogs required daily maintenance therapy, 7 every other day, 6 twice weekly and 5 dogs required additional therapy. Coat length did not influence the results. No adverse effects or changes to blood parameters were noted. HCA spray proved safe and effective up to 70 days. It is not, however, licensed for long-term treatment.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19374721/