Peer-reviewed veterinary case report
New metaflumizone flea treatment controls fleas on cats for weeks
By Holzmer, S et al.·Published in Veterinary parasitology·2007·Fort Dodge Animal Health, United States·View original on PubMed →
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Original publication title: Efficacy of a novel formulation of metaflumizone for the control of fleas (Ctenocephalides felis) on cats.
- Species:
- cat
Plain-English summary
A group of domestic shorthair cats was treated with a new flea medication called metaflumizone to see how well it worked against fleas. After applying the treatment, the cats were infested with fleas weekly for about two months. The results showed that metaflumizone significantly reduced the number of fleas on the cats, providing over 90% control for up to seven weeks after just one application. This means that if your cat has a flea problem, metaflumizone could be an effective option to consider.
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Abstract
A novel spot-on formulation containing metaflumizone (ProMeris for Cats, Fort Dodge Animal Health, Overland Park, KS) was evaluated in five laboratory studies to determine the duration of residual efficacy in cats against fleas after a single spot treatment. In each study, eight domestic shorthair cats were randomly allocated to each treatment group and individually housed. One group in each study remained non-treated. In one study, an additional group of eight cats was treated with a placebo formulation. Cats were treated topically with metaflumizone formulation to provide a dose of at least 40mg metaflumizone/kg. Cats were infested with 100 cat fleas (Ctenocephalides felis felis) once per week for approximately 8 weeks. Cats were comb counted 48h after treatment and each infestation to determine the number of viable fleas present. There were no significant differences in flea counts between the non-treated control and the placebo-treated control (P>0.05) other than a 26% reduction at week 1, demonstrating that the formulation excipients had no activity. Metaflumizone treatment resulted in significantly lower flea numbers relative to non-treated controls on all post-treatment count days (P<0.05). Metaflumizone provided >90% control of flea infestations up to 7 weeks following a single treatment.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17931782/