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Peer-reviewed veterinary case report

New topical treatment kills brown dog ticks on cats

By Tielemans, Eric et al.·Published in Parasite (Paris, France)·2021·Boehringer-Ingelheim Animal Health, France·View original on PubMed

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Original publication title: Efficacy of a novel topical combination of esafoxolaner, eprinomectin and praziquantel against Rhipicephalus sanguineus in cats.

Species:
cat

Plain-English summary

A group of 20 cats with tick infestations were treated with a new topical medication that combines three ingredients: esafoxolaner, eprinomectin, and praziquantel. After just one treatment, the cats showed a 90% reduction in existing ticks within 48 hours, and the medication prevented new infestations for at least six weeks with a success rate of 96%. This means that the cats were able to stay tick-free after the initial treatment. If your cat has ticks, this new treatment could be very effective in getting rid of them and keeping them away.

People also search for: cat tick treatment · esafoxolaner for cats · how to get rid of ticks on cats

Abstract

Esafoxolaner is a purified enantiomer of afoxolaner with insecticidal and acaricidal properties. It is combined with eprinomectin and praziquantel in a novel topical endectoparasiticide formulation for cats. The efficacy of this novel formulation was assessed in an experimental study against induced infestation of Rhipicephalus sanguineus ticks. Twenty cats were randomly allocated to either a placebo control group or a treated group in a 1:1 ratio. Infested cats were treated topically once at the minimum recommended dose. The study was designed to assess curative efficacy 48 h after treatment and to test preventive efficacy 48 h after weekly infestations for 2 months. At each weekly infestation, all cats were infested with 25 male and 25 unfed female R. sanguineus ticks. At each tick count, at least 6 in 10 control cats had a retention of 13 (26%) or more live ticks, demonstrating adequate infestation throughout the study. Curative efficacy on existing tick infestation was 90%; preventive efficacy over the following 6 weeks was at least 96%.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33812456/