Peer-reviewed veterinary case report
New topical treatment for ear mites in cats works well
By Tielemans, Eric et al.·Published in Parasite (Paris, France)·2021·Boehringer-Ingelheim Animal Health, France·View original on PubMed →
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Original publication title: Efficacy of a novel topical combination of esafoxolaner, eprinomectin and praziquantel against ear mite (Otodectes cynotis) infestations in cats.
- Species:
- cat
Plain-English summary
A group of cats with ear mites (Otodectes cynotis) were treated with a new topical medication called NexGardCombo, which combines three active ingredients. In studies conducted in South Africa, the USA, and Europe, the treatment showed over 97% effectiveness in eliminating the mites after one month. All cats were confirmed to have ear mites before treatment, and no health issues were reported from using the medication. This new treatment appears to be a highly effective option for managing ear mite infestations in cats.
People also search for: cat ear mites treatment · NexGardCombo for cats · how to get rid of ear mites in cats
Abstract
Esafoxolaner, a purified enantiomer of afoxolaner with insecticidal and acaricidal properties, is combined with eprinomectin and praziquantel, nematodicidal and cestodicidal compounds, in NexGardCombo, a novel topical endectoparasiticide formulation for cats. The efficacy of this formulation was assessed against Otodectes cynotis in two laboratory studies conducted in South Africa and in the USA with local isolates, and in one field trial conducted in Europe. In each study, cats were randomly allocated to a placebo-treated control group and a novel formulation-treated group. In the laboratory studies, cats were treated at the minimum recommended dose; in the field trial, cats were treated at label dose. All included cats were diagnosed positive for O. cynotis prior to treatment by otoscopy. The main variable of efficacy was a comparison of the number of live O. cynotis collected in both ear canals of all cats in the treated and control groups, one month after treatment. Efficacy of the novel topical formulation exceeded 97% in the three studies. These studies demonstrated the high effectiveness of NexGardCombo in cats for the treatment of O. cynotis infestations. No health abnormalities were attributed to the treatment in any of the studies.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33812458/