Peer-reviewed veterinary case report
New topical treatment kills Echinococcus tapeworms in cats
By Prullage, Joe et al.·Published in Parasite (Paris, France)·2021·Boehringer-Ingelheim Animal Health, United States·View original on PubMed →
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Original publication title: Efficacy of a novel topical combination of esafoxolaner, eprinomectin and praziquantel against Echinococcus multilocularis infections in cats.
- Species:
- cat
Plain-English summary
A group of cats was tested for a serious parasite infection called Echinococcus multilocularis, which can cause health issues. They were treated with a new topical medication called NexGardCombo, which combines three active ingredients to fight both internal and external parasites. After treatment, none of the cats that received the medication had any signs of the parasite, showing that the treatment was completely effective. This means that NexGardCombo could be a great option for preventing this type of infection in cats.
People also search for: cat Echinococcus infection treatment · NexGardCombo for cats · how to treat parasites in cats
Abstract
NexGardCombo, a novel topical endectoparasiticide formulation for cats combining esafoxolaner, eprinomectin and praziquantel, for the treatment of internal and external parasite infestations, including arthropods, nematodes and cestodes, was tested for efficacy against induced infections of Echinococcus multilocularis in cats, in two experimental studies. The two studies were performed in the United States with the same E. multilocularis isolate sourced locally. In each study, 20 cats were inoculated intra-gastrically with ~30,000 E. multilocularis protoscoleces three weeks before treatment, then ten cats were randomly allocated to a placebo control group or to the novel formulation treated group. Inoculated cats were treated topically once at the minimum recommended dose of the novel formulation, or with an identical volume of placebo. One week after treatment, cats were humanely euthanized for parasite recovery and count. The efficacy calculation was based on comparison of number of scoleces found in the control group and the novel formulation group. In the two control groups, E. multilocularis scoleces were found in five (range: 30-1025) and eight (range 2-345) cats, the geometric means inclusive of the ten cats per group were 8.9 and 28.8, respectively. In the two novel formulation-treated groups, none of the cats harbored any E. multilocularis scoleces, demonstrating 100% efficacy.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33812461/