Peer-reviewed veterinary case report
Topical fipronil, amitraz, and methoprene kills brown dog ticks
By Hunter, James S et al.·Published in Veterinary parasitology·2011·Merial Limited, United States·View original on PubMed →
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Original publication title: Efficacy of a novel topical combination of fipronil, amitraz and (S)-methoprene for treatment and control of induced infestations of brown dog ticks (Rhipicephalus sanguineus) on dogs.
- Species:
- dog
Plain-English summary
A group of dogs was treated with a new topical product containing fipronil, amitraz, and (S)-methoprene to control brown dog ticks. After just one application, the treatment showed impressive results, killing up to 93% of ticks within the first 12 hours and maintaining over 96% effectiveness for at least 35 days. This means that if your dog is dealing with a tick problem, this combination treatment could provide quick and lasting relief from these pests.
People also search for: dog tick treatment · brown dog ticks in dogs · how to get rid of ticks on dogs
Abstract
Four laboratory studies were conducted to demonstrate that a single topical dose of a novel spot-on combination containing fipronil, amitraz and (S)-methoprene (CERTIFECT™, Merial Limited, GA, USA) is efficacious against the brown dog tick, Rhipicephalus sanguineus. In each study, 6-8 male and 6-8 female purpose-bred, laboratory mongrels, terrier cross or Beagles were randomly assigned to one of two study groups (treated and untreated), based on pre-treatment parasite counts. Starting on the day before treatment, each dog was infested weekly with 50 ticks. Ticks were thumb counted at various time points after treatment and weekly infestations starting as early as 6h and continued at 12, 18 and 24h depending on the study. Ticks were removed and counted at 48 h after treatment and weekly infestations. CERTIFECT provided rapid and excellent control of pre-existing and newly acquired infestations of R. sanguineus with efficacy as high as 93% within the first 12h after a single topical treatment. Excellent control (>96%) of R. sanguineus as early as 18 h, following post treatment infestations was maintained for at least 35 days.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21777733/