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Peer-reviewed veterinary case report

Topical treatment stops hookworm infections in cats

By Prullage, Joseph B et al.·Published in Veterinary parasitology·2014·Merial Ltd., United States·View original on PubMed

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Original publication title: Efficacy of a novel topical combination of fipronil, (S)-methoprene, eprinomectin and praziquantel against induced infections of Ancylostoma spp. nematodes of cats.

Species:
cat

Plain-English summary

A group of cats was treated with a new topical medication that combines fipronil, (S)-methoprene, eprinomectin, and praziquantel to fight hookworm infections caused by Ancylostoma species. The studies showed that this treatment was highly effective, eliminating 100% of the hookworms in most cases and 99.5% in one instance. This means that if your cat has a hookworm infection, this new treatment could be a very effective option to consider. Always consult your veterinarian for the best course of action for your pet's health.

People also search for: cat hookworm treatment · fipronil for cats · praziquantel for cat worms

Abstract

Four studies were conducted to examine the efficacy of a novel topical combination of fipronil, (S)-methoprene, eprinomectin, and praziquantel (BROADLINE(®), Merial) against Ancylostoma tubaeforme and Ancylostoma braziliense hookworms of cats. In each study, purpose-bred cats were randomly assigned to treatment groups of 10 or 12 cats per group. In three studies the cats were inoculated with A. tubaeforme and in one study with A. braziliense. The inoculations were undertaken on a schedule which resulted in the hookworms reaching the fourth larval stage in two of the studies, or the adult stage in four of the studies, by the day of treatment. In each study there was also an untreated control and 1 or 2 groups treated with the novel combination. In the two studies where efficacy against the fourth larval stage of A. tubaeforme was tested, the efficacy recorded was 100%. In the three studies where efficacy against the adult stage of A. tubaeforme was tested, efficacy of 100% was also confirmed. In the study where efficacy against the adult stage of A. braziliense was tested efficacy was 99.5%.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24703073/