Peer-reviewed veterinary case report
Spot-on fluralaner plus moxidectin treats mange in pet rabbits
By d'Ovidio, Dario & Santoro, Domenico·Published in Veterinary dermatology·2023·Private practitioner, Italy·View original on PubMed →
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Original publication title: Efficacy of a spot-on combination of fluralaner plus moxidectin against naturally acquired Sarcoptes scabiei infestation in 10 pet rabbits: Retrospective case series.
- Species:
- rabbit
Plain-English summary
Ten pet rabbits suffering from sarcoptic mange, which causes severe itching and skin lesions, were treated with a single application of a spot-on combination of fluralaner and moxidectin. Within 21 days, all rabbits showed complete recovery, with no signs of mites or skin problems. The treatment was effective, and none of the rabbits experienced a relapse within 90 days of the treatment. This suggests that this combination treatment is a reliable option for managing sarcoptic mange in rabbits.
People also search for: rabbit skin problems treatment · sarcoptic mange in rabbits · fluralaner moxidectin for rabbits
Abstract
BACKGROUND: Current treatments for sarcoptic mange in rabbits mainly include administration of avermectines every 10-30 days. Recently, a single oral dose of fluralaner has been shown to be effective to treat sarcoptic mange in 12 pet rabbits over a three-month period. OBJECTIVES: To retrospectively assess the efficacy of a spot-on combination of fluralaner plus moxidectin (Bravecto Plus) for the treatment of sarcoptic mange in rabbits. ANIMALS: Ten client-owned rabbits diagnosed with sarcoptic mange. MATERIALS AND METHODS: An application of fluralaner plus moxidectin at an average dose of 25 mg/kg and 1.24 mg/kg, respectively, was administered topically once. Parasitological and dermatological examination was carried out weekly for one month and monthly for three months. RESULTS: The median age at diagnosis was 15 (range 3-48) months. Based on the age of onset, there were three juvenile (<6-month-old) and seven adult-onset cases. Of those, four were generalized (head, feet and/or genital area) and six were localized form (head only). The combination of fluralaner plus moxidectin resulted in 100% eradication of mites and complete resolution of all skin lesions within 21 days. Recurrence was not observed 90 days post-treatment. Relapse was not observed in one case followed up for a further four months and two rabbits followed up for a further six months. The other pets were lost to follow-up. CONCLUSIONS AND CLINICAL RELEVANCE: These results indicated that a single dose of a formulation containing fluralaner plus moxidectin, at 25 mg/kg and 1.24 mg/kg, respectively, was effective for the treatment of naturally occurring sarcoptic mange in rabbits.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36062517/