Peer-reviewed veterinary case report
Afoxolaner pill kills Dermacentor variabilis ticks on dogs for 30 days
By Mitchell, Elizabeth B et al.·Published in Veterinary parasitology·2014·Merial Limited, United States·View original on PubMed →
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Original publication title: Efficacy of afoxolaner against Dermacentor variabilis ticks in dogs.
- Species:
- dog
Plain-English summary
A group of beagle dogs was treated with a new oral medication called afoxolaner to eliminate and control ticks. After being infested with ticks, the dogs received a single dose of afoxolaner, which proved highly effective, killing nearly all ticks within two days and keeping them away for up to 30 days. This treatment showed over 99% effectiveness against the ticks, making it a reliable option for tick control in dogs.
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Abstract
Efficacy of afoxolaner, a novel isoxazoline insecticide/acaricide, against Dermacentor variabilis ticks was confirmed in two laboratory studies. Each study utilized a controlled, randomized block design. One day prior to treatment, beagle dogs were infested with 50 unfed adult ticks. Repeat infestations were performed weekly for four weeks. The number of live ticks remaining on each dog was determined 48 h after treatment and after each subsequent infestation. A single oral treatment with a dose approaching the minimum effective dose of afoxolaner (2.5mg/kg) eliminated the pre-existing infestations by D. variabilis ticks and controlled weekly re-infestations with 99.7-100% efficacy up to Day 23 and >97% efficacy at Day 30.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24629426/