Peer-reviewed veterinary case report
Afoxolaner pill kills blacklegged ticks on dogs for 30 days
By Mitchell, Elizabeth B et al.·Published in Veterinary parasitology·2014·Merial Limited, United States·View original on PubMed →
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Original publication title: Efficacy of afoxolaner against Ixodes scapularis ticks in dogs.
- Species:
- dog
Plain-English summary
A group of beagle dogs was treated with a new oral medication called afoxolaner to see how well it worked against ticks. The dogs were infested with ticks before treatment, and after taking afoxolaner, it eliminated nearly all the ticks and kept them away for weeks. The treatment showed over 98% effectiveness in controlling the ticks for almost a month. This means that afoxolaner is a strong option for keeping dogs tick-free.
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Abstract
Efficacy of afoxolaner, a novel isoxazoline insecticide/acaricide, against Ixodes scapularis was evaluated in a laboratory study. One day prior to treatment, beagle dogs (n=16) were infested with 50 unfed wild adult ticks. Repeat infestations were performed weekly for four additional weeks. The number of live ticks remaining on each dog was determined 48 h after treatment and after each subsequent infestation. A single oral treatment with a dose approaching the minimum effective dose of afoxolaner (2.5mg/kg) eliminated the pre-existing infestations of I. scapularis ticks and controlled weekly re-infestations, with efficacy between 98% and 100% recorded until Day 23 and 94% at Day 30.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24685321/