Peer-reviewed veterinary case report
Efficacy of afoxolaner against Ixodes scapularis ticks in dogs.
- Journal:
- Veterinary parasitology
- Year:
- 2014
- Authors:
- Mitchell, Elizabeth B et al.
- Affiliation:
- Merial Limited · United States
- Species:
- dog
Abstract
Efficacy of afoxolaner, a novel isoxazoline insecticide/acaricide, against Ixodes scapularis was evaluated in a laboratory study. One day prior to treatment, beagle dogs (n=16) were infested with 50 unfed wild adult ticks. Repeat infestations were performed weekly for four additional weeks. The number of live ticks remaining on each dog was determined 48 h after treatment and after each subsequent infestation. A single oral treatment with a dose approaching the minimum effective dose of afoxolaner (2.5mg/kg) eliminated the pre-existing infestations of I. scapularis ticks and controlled weekly re-infestations, with efficacy between 98% and 100% recorded until Day 23 and 94% at Day 30.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/24685321/