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Peer-reviewed veterinary case report

Afoxolaner (NexGard) kills chewing lice in naturally infested dogs

By Mihalca, Andrei Daniel et al.·Published in Parasites & vectors·2022·Department of Parasitology and Parasitic Diseases·View original on PubMed

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Original publication title: Efficacy of afoxolaner (NexGard®) against natural infestations with Trichodectes canis in dogs under field conditions.

Species:
dog

Plain-English summary

A group of dogs infested with chewing lice (Trichodectes canis) were treated with either a chewable tablet containing afoxolaner (NexGard) or a control product. After 14 days, no living lice were found on any of the dogs, and by day 30, both groups showed no lice, although some eggs were still present in the control group. This study suggests that afoxolaner is highly effective in eliminating chewing lice in dogs. If your dog has lice, talk to your vet about using NexGard for treatment.

People also search for: dog chewing lice treatment · NexGard for dogs · how to get rid of dog lice

Abstract

BACKGROUND: Trichodectes canis is a small chewing louse found globally that primarily infests dogs. Limited information is available on the efficacy of isoxazolines against infestation with the chewing louse. In the present study, we evaluated the efficacy of afoxolaner, an isoxazoline class compound, in naturally infested domestic dogs. METHODS: The field study was carried out in Romania. Between September 2021 and December 2021, 43 dogs with confirmed T. canis infestation were included in the study. On the day of the inclusion (day 0), each animal was clinically examined and randomly treated with a control product labeled for use against lice [fipronil-(S)-methoprene combination (Frontline Combo®; Boehringer Ingelheim)] or with the investigational product [chewable tablets containing afoxolaner (NexGard®; isoxazoline)]. Each animal was evaluated for the presence of lice at 15 and 30 days post-inclusion. RESULTS: Of the 48 dogs initially included in the study, 43 completed the treatment period [18 in the control group (CG) and 25 in the investigational group (IG)]. At day 14, no living T. canis lice were detected on the dogs in either group. At day 14, dead lice were detected in four dogs in the IG, while eggs were present in two dogs in the IG and in one dog in the CG. At day 30, no lice were detected in either group, while eggs were still present in one dog in the CG. CONCLUSION: These results suggest that afoxolaner is a feasible treatment option against chewing lice in dogs, providing 100% curative efficacy.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36071527/