Peer-reviewed veterinary case report
P128 protein gel healed antibiotic-resistant dog skin infections in 8
By Junjappa, Raghu Patil et al.·Published in Veterinary research communications·2013·Gangagen Biotechnologies Pvt. Ltd., India·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Efficacy of anti-staphylococcal protein P128 for the treatment of canine pyoderma: potential applications.
- Species:
- dog
Plain-English summary
Seventeen dogs with skin infections known as pyoderma were treated with a new protein-based gel called P128. These dogs had been suffering from painful, infected skin caused by Staphylococcus bacteria, which were resistant to many common antibiotics. After applying the P128 gel twice a day for eight days, all the dogs showed complete healing of their skin lesions. This suggests that P128 could be an effective treatment option for dogs with this type of infection.
People also search for: dog skin infection treatment · pyoderma in dogs · P128 for dog skin problems · antibiotic-resistant skin infection in dogs
Abstract
In this study, we demonstrate the antibacterial activity of P128 on Staphylococcus isolates responsible for canine pyoderma. Eighty seven swabs were collected from dogs suffering from pyoderma and subjected to antibiotic sensitivity test and 46 Staphylococcus strains were isolated and characterized. In-vitro antimicrobial susceptibility testing with P128 was done by Minimum Inhibitory Concentration (MIC) method as per CLSI guidelines. All the Staphylococci isolated from the dogs with pyoderma, although showed resistance to various antibiotics tested, were lysed by P128. Clinical efficacy of P128 was examined in 17 dogs with pyoderma by application of the P128 hydrogel twice daily for 8 days and the results indicated complete healing of all the lesions of all the dogs under treatment. Under the conditions of this study, P128 was found to be a potent convenient proteinaceous drug for the treatment of staphylococcal pyoderma in dogs.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23661290/