Peer-reviewed veterinary case report
Efficacy of Bacteriophages in a Staphylococcus aureus Nondiabetic or Diabetic Foot Infection Murine Model.
- Journal:
- Antimicrobial agents and chemotherapy
- Year:
- 2020
- Authors:
- Albac, S et al.
- Affiliation:
- Vivexia · France
Abstract
This study investigated theefficacy of three bacteriophages combined compared with linezolid in two mouse models (nondiabetic and diabetic) offoot infection. In both models, a single injection of bacteriophages in the hindpaw showed significant antibacterial efficacy. Linezolid was as effective as bacteriophages in nondiabetic animals but ineffective in diabetic animals. These findings further support preclinical and clinical studies for the development of phage therapy.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/31712203/