Peer-reviewed veterinary case report
Collagen matrix improves success of glaucoma valve surgery in dogs
By Hong, Won-Gyun et al.·Published in Veterinary ophthalmology·2021·Department of Veterinary Surgery, South Korea·View original on PubMed →
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Original publication title: Efficacy of biodegradable collagen matrix (OlogenCM) in augmenting the success rate of Ahmed glaucoma valve implantation in canine glaucoma.
- Species:
- dog
Plain-English summary
Five dogs with uncontrolled glaucoma underwent surgery to implant an Ahmed glaucoma valve (AGV) along with a biodegradable collagen matrix called ologen. After the procedure, the dogs showed a significant drop in eye pressure, going from an average of 47 mmHg to just 17 mmHg after six months. All five dogs maintained healthy eye pressure levels, and the need for anti-glaucoma eye drops decreased significantly. This approach appears to be safe and effective for managing glaucoma in dogs, helping them maintain better eye health without major complications.
People also search for: dog glaucoma treatment · Ahmed glaucoma valve for dogs · ologen collagen matrix for dogs
Abstract
OBJECTIVE: To prospectively assess the efficacy of a biodegradable collagen matrix (ologen) in dogs with uncontrolled glaucoma receiving an Ahmed glaucoma valve (AGV) implant. ANIMAL STUDIED: Five client-owned dogs with glaucoma (five eyes). PROCEDURES: Five eyes treated for uncontrolled glaucoma underwent AGV implantation with ologen. Ologen was placed on the AGV plate and tube with a scleral flap. Complete ophthalmological examinations were performed preoperatively and at 1 and 3 days, 1 and 2 weeks, and 1, 2, 3, and 6 months postoperatively. Surgical outcomes were assessed based on the intraocular pressure (IOP), vision, frequency of anti-glaucoma eye drops, and bleb morphology; complications, if any, were recorded. The number of dogs with an IOP <20 mmHg with or without topical medications were tabulated and compared to those with an IOP ≥20 mmHg or those requiring surgery to maintain the IOP at <20 mmHg. RESULTS: The IOP significantly decreased from 47.00 ± 5.09 mmHg preoperatively to 17.00 ± 0.71 mmHg 6 months postoperatively (p = .008). IOP was controlled (<20 mmHg) in 5/5 dogs at 6 months postoperatively. Brief periods of elevated IOP (IOP ≥ 20 mmHg, IOP spike) occurred in one eye (case 5) at 1 month (35 mmHg) and 2 months (33 mmHg) postoperatively. The anti-glaucoma eye drop frequency decreased from 3.2 ± 0.44 preoperatively to 1.6 ± 0.90 at 6 months postoperatively (p = .007). CONCLUSIONS: To our knowledge, this is the first study to assess the potential safety of AGV implantation with ologen for canine glaucoma. This method effectively controlled the IOP, without any adverse effects.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34240540/