Peer-reviewed veterinary case report
Topical flea treatments tested on dogs and cats in Tampa homes
By Dryden, Michael W et al.·Published in Veterinary parasitology·2011·Kansas State University, United States·View original on PubMed →
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Original publication title: Efficacy of dinotefuran-pyriproxyfen, dinotefuran-pyriproxyfen-permethrin and fipronil-(S)-methoprene topical spot-on formulations to control flea populations in naturally infested pets and private residences in Tampa, FL.
Plain-English summary
A group of 13 cats and 7 dogs in Tampa, Florida, were treated for flea infestations using different topical treatments. One group received a combination of dinotefuran and pyriproxyfen, while another group was treated with fipronil and methoprene. Within just a week, both treatments significantly reduced flea populations on the pets by over 87%. After two monthly applications, flea burdens were reduced by more than 95%, and indoor flea counts also dropped dramatically. These treatments proved effective in controlling fleas both on pets and in their homes.
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Abstract
Thirteen cats and 7 dogs living in 14 homes were treated topically with either a dinotefuran (22%, w/w)/pyriproxyfen (3.00%, w/w) (DP) or dinotefuran (4.95%, w/w)/pyriproxyfen (0.44%, w/w)/permethrin (36.08%, w/w) (DPP) topical spot-on, respectively. Twenty cats and 7 dogs living in 16 homes were treated topically with either a fipronil (9.8%, w/w)/(S)-methoprene (11.8%, w/w) or fipronil (9.8%, w/w)/(S)-methoprene (8.8%, w/w) topical spot-on (FM), respectively. All products were applied according to label directions by study investigators on day 0 and again between days 28 and 30. Flea populations on pets were assessed using visual area counts and premise flea infestations were assessed using intermittent-light flea traps on days 0, 7, 14, 21, 28-30, 40-45, and 54-60. A single application of the DP-DPP and FM formations reduced flea populations by 87.35% and 88.44%, respectively within 7 days. Following two monthly applications of either the DP-DPP or FM formulations, pet flea burdens were reduced by 95.24% and 95.47%, respectively. Flea numbers in the indoor-premises were also markedly reduced by days 54-60, with 98.05% and 96.15% reductions in intermittent-light flea trap counts in the DP-DPP or FM treatment groups, respectively.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21705147/