Peer-reviewed veterinary case report
Profender tablets effectively treat roundworm infections in dogs
By Altreuther, Gertraut et al.·Published in Parasitology research·2009·Bayer Animal Health GmbH, Germany·View original on PubMed →
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Original publication title: Efficacy of emodepside plus praziquantel tablets (Profender tablets for dogs) against mature and immature infections with Toxocara canis and Toxascaris leonina in dogs.
- Species:
- dog
Plain-English summary
A group of dogs infected with roundworms (Toxocara canis and Toxascaris leonina) was treated with Profender tablets, which contain emodepside and praziquantel. The treatment was highly effective, eliminating over 99% of adult worms and more than 92% of immature stages. No side effects were reported, making this a safe and effective option for treating these common worm infections in dogs.
People also search for: dog roundworm treatment · Profender tablets for dogs · Toxocara canis symptoms in dogs
Abstract
The efficacy of emodepside plus praziquantel tablets (Profender tablets for dogs) against mature adult, immature adult and larval stages of Toxocara canis and Toxascaris leonina was evaluated in ten randomised, blinded and placebo-controlled dose confirmation studies in naturally or experimentally infected dogs. The tablets were used at the proposed minimum dose of 1 mg emodepside and 5 mg praziquantel per kg body weight. Efficacy was calculated based on worm counts after necropsy. Five studies demonstrated >99% efficacy against mature adult, >92% efficacy against immature adult, >98% efficacy against L4 and >94% efficacy against L3 larval stages of T. canis. Another five studies demonstrated >99% efficacy against mature and immature adult and >95% efficacy against L4 larval stages of T. leonina. No side effects of the treatment were observed. Emodepside plus praziquantel tablets thus provide a comprehensive new treatment option for ascarid infections in the dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19575219/