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Peer-reviewed veterinary case report

Safe and effective Profender tablets treat hookworms in dogs

By Schimmel, Annette et al.·Published in Parasitology research·2009·Bayer Animal Health GmbH, Germany·View original on PubMed

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Original publication title: Efficacy of emodepside plus praziquantel tablets (Profender tablets for dogs) against mature and immature adult Ancylostoma caninum and Uncinaria stenocephala infections in dogs.

Species:
dog

Plain-English summary

A group of dogs with hookworm infections were treated with a new flavored tablet that combines emodepside and praziquantel. This treatment was found to be over 95% effective against one type of hookworm and over 98% effective against another type, with no side effects reported. The dogs showed significant improvement after receiving the medication, making it a safe and effective option for treating these infections.

People also search for: dog hookworm treatment · emodepside praziquantel for dogs · symptoms of hookworms in dogs

Abstract

This paper reports the efficacy of a novel flavoured tablet formulation of emodepside plus praziquantel (Profender tablets for dogs) against mature and immature adult hookworms (Ancylostoma caninum and Uncinaria stenocephala) in dogs. The tablets were used at the minimum recommended dose of 1 mg emodepside and 5 mg praziquantel per kg body weight. Four randomised, blinded and controlled laboratory studies demonstrated >95% efficacy against mature and immature adult stages of U. stenocephala and four randomised, blinded and controlled laboratory studies demonstrated >98% efficacy against mature and immature adult stages of A. caninum. No side effects of the treatment were observed. It is concluded that the emodepside plus praziquantel tablet is an effective and safe treatment against mature and immature hookworms.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19575220/