Peer-reviewed veterinary case report
Profender tablets effectively treat whipworm infections in dogs
By Schimmel, Annette et al.·Published in Parasitology research·2009·Bayer Animal Health GmbH, Germany·View original on PubMed →
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Original publication title: Efficacy of emodepside plus praziquantel tablets (Profender tablets for dogs) against mature and immature adult Trichuris vulpis infections in dogs.
- Species:
- dog
Plain-English summary
A group of dogs with whipworm infections (Trichuris vulpis) were treated with a new flavored tablet called Profender, which contains emodepside and praziquantel. In studies, this treatment showed over 99% effectiveness in eliminating both mature and immature whipworms without causing any side effects. The recommended dose was found to be safe and effective for treating these infections in dogs.
People also search for: dog whipworm treatment · Profender tablets for dogs · symptoms of whipworm in dogs
Abstract
This paper reports on the efficacy of a novel flavoured tablet formulation of emodepside plus praziquantel (Profender tablets for dogs) against mature and immature adult whipworms (Trichuris vulpis) at the proposed minimum dose of 1 mg emodepside and 5 mg praziquantel per kg body weight in dogs. Three randomised, blinded and controlled laboratory studies with naturally or experimentally infected dogs were performed. The first study was conducted as a dose determination study in experimentally infected dogs using three different dose levels, i.e., 0.5x, 1x and 2x the minimum therapeutic dose. Two further studies confirmed the efficacy of emodepside plus praziquantel tablets against mature and immature adult T. vulpis at the recommended minimum dose. In all three studies, the efficacy against mature and immature adult T. vulpis was >99%. No side effects of the treatment were observed. It is concluded that the emodepside plus praziquantel tablet is an effective and safe treatment against mature and immature adult stages of T. vulpis in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19575221/