Peer-reviewed veterinary case report
Emodepside plus toltrazuril kills common intestinal worms in dogs
By Schimmel, Annette et al.Ā·Published in Parasitology researchĀ·2011Ā·Bayer Animal Health GmbH, GermanyĀ·View original on PubMed ā
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Original publication title: Efficacy of emodepside plus toltrazuril (Procox(®) oral suspension for dogs) against Toxocara canis, Uncinaria stenocephala and Ancylostoma caninum in dogs.
- Species:
- dog
Plain-English summary
A group of dogs with intestinal worm infections, including Toxocara canis (roundworms) and hookworms, were treated with a medication called emodepside plus toltrazuril (Procox). This treatment was found to be highly effective, eliminating nearly all adult worms and significantly reducing immature worms as well. The studies showed that the medication worked safely and effectively in all treated dogs, providing a strong option for pet owners dealing with these common parasites.
People also search for: dog roundworm treatment Ā· hookworm treatment for dogs Ā· Procox for dog worms
Abstract
The efficacy of emodepside plus toltrazuril (Procox® oral suspension for dogs) against different species of gastrointestinal nematodes (Toxocara canis, Ancylostoma caninum, Uncinaria stenocephala) was evaluated in nine randomised,blinded and placebo-controlled laboratory studies in naturally or experimentally infected dogs. The product was used at the proposed minimum dose of 0.45 mg emodepside and 9 mg toltrazuril per kg body weight. Efficacy was calculated based on worm counts after necropsy. Worm burdens in the control dogs ranged between 0 and 409 worms of the respective stage for T. canis and between 4 and 655 worms for hookworms. The studies demonstrated 100 % efficacy of emodepside/toltrazuril suspension against mature adult, ≥ 94.7 %efficacy against immature adult and 99.3 % efficacy against the L4 larval stage of T. canis. The efficacy against mature adult A. caninum was ≥ 99.5 % and the efficacy against mature adult U. stenocephala was 100 %. All differences between treatment and control groups were statistically significant and no gender effect was found. It can be concluded that the emodepside/toltrazuril suspension represents a safe and highly effective product in dogs with nematode (T. canis, hookworms) infection.
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Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21739370/