Peer-reviewed veterinary case report
Feline anti-parvovirus antibodies tested for treating dog parvovirus
By Gerlach, M. et al.·Published in Journal of Small Animal Practice·2017·Clinic of Small Animal Medicine Centre for Clinical Veterinary Medicine 80539 Munich Germany, Germany·View original on Crossref →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Efficacy of feline anti‐parvovirus antibodies in the treatment of canine parvovirus infection
- Species:
- dog
Plain-English summary
A group of 31 dogs with canine parvovirus infection, showing symptoms like vomiting and diarrhea, were treated with either feline anti-parvovirus antibodies or a placebo. Despite initial hopes that these feline antibodies could help dogs recover from parvovirus, the study found no significant differences in recovery times or overall health between the two groups. Both groups showed some improvement over time, but the treatment with feline antibodies did not provide any additional benefits. Ultimately, the study concluded that the feline antibodies were not effective for treating canine parvovirus in the dosage used.
People also search for: dog parvovirus treatment · canine parvovirus symptoms · feline antibodies for dogs · dog vomiting diarrhea treatment
Abstract
ObjectiveThis prospective, randomised, placebo‐controlled, double‐blinded study aimed to evaluate efficacy of commercially available feline anti‐parvovirus antibodies in dogs with canine parvovirus infection.MethodsFirst, cross‐protection of feline panleukopenia virus antibodies against canine parvovirus was evaluated in vitro. In the subsequent prospective clinical trial, 31 dogs with clinical signs of canine parvovirus infection and a positive faecal canine parvovirus polymerase chain reaction were randomly assigned to a group receiving feline panleukopenia virus antibodies (n=15) or placebo (n=16). All dogs received additional routine treatment. Clinical signs, blood parameters, time to clinical recovery and mortality were compared between the groups. Serum antibody titres and quantitative faecal polymerase chain reaction were compared on days 0, 3, 7, and 14.ResultsIn vitro, canine parvovirus was fully neutralised by feline panleukopenia virus antibodies. There were no detected significant differences in clinical signs, time to clinical recovery, blood parameters, mortality, faecal virus load, or viral shedding between groups. Dogs in the placebo group showed a significant increase of serum antibody titres and a significant decrease of faecal virus load between day 14 and day 0, which was not detectable in dogs treated with feline panleukopenia virus antibodies.Clinical SignificanceNo significant beneficial effect of passively transferred feline anti‐parvovirus antibodies in the used dosage regimen on the treatment of canine parvovirus infection was demonstrated.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on Crossref: https://doi.org/10.1111/jsap.12676