Peer-reviewed veterinary case report
Tick control on dogs using fipronil + methoprene versus imidacloprid
By Dryden, M W et al.·Published in Veterinary therapeutics : research in applied veterinary medicine·2008·Kansas State University.·View original on PubMed →
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Original publication title: Efficacy of fipronil (9.8% w/w) + (S)-methoprene (8.8% w/w) and imidacloprid (8.8% w/w) + permethrin (44% w/w) against Dermacentor variabilis (American dog tick) on dogs.
- Species:
- dog
Plain-English summary
A group of dogs infested with American dog ticks were treated with two different topical solutions to see which was more effective at getting rid of the ticks. The first solution, containing fipronil and (S)-methoprene, worked significantly better, keeping more dogs free of live ticks throughout the study. The second solution, which included imidacloprid and permethrin, showed some effectiveness but only for a limited time and did not keep dogs free of ticks as well as the first treatment. Overall, the fipronil and (S)-methoprene combination proved to be the more reliable option for tick control.
People also search for: dog tick treatment · fipronil for dogs · imidacloprid permethrin effectiveness
Abstract
This study evaluated overall efficacy, percentage of dogs free of live ticks, retention of ticks, and efficacy against retained ticks of fipronil (9.8% w/w) + (S)-methoprene (8.8% w/w) and imidacloprid (8.8% w/w) + permethrin (44% w/w) spot-on topical solutions against Dermacentor variabilis-infested dogs. Tick control was significantly greater (P < .05) on dogs treated with fipronil + (S)-methoprene than on control dogs for the entire 30-day study period. Conversely, the combination product of imidacloprid + permethrin demonstrated activity significantly (P < .05) different from that seen on control dogs only up to day 23. Significantly (P < .05) more dogs treated with fipronil + (S)-methoprene were free of live ticks compared with controls on days 3, 9, and 16. There was never a significant difference (P > .05) between control and imidacloprid + permethrin-treated dogs in numbers of dogs free of live ticks. After the initial 10-minute tick exposure, lower numbers of ticks were retained on the imidacloprid + permethrin-treated dogs than on the fipronil + (S)-methoprene-treated dogs. However, when evaluating the effectiveness of the acaricides on "retained ticks," it appears that while some of the ticks were rapidly knocked down on the imidacloprid + permethrin-treated dogs, efficacy against ticks still retained at 10 minutes was never greater than 50%.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18415943/